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Title: Prevalence and correlates of asthma among 12-14 year old school children in a district and their quality life
Authors: Danansuriya, MN
Issue Date: 22-Sep-2009
Publisher: Post Graduate of Medicine (PGIM), University of Colombo, Sri Lanka
Citation: Danansuriya, MN. Prevalence and correlates of asthma among 12-14 year old school children in a district and their quality life. [Thesis for MD ( Community Medicine)] 2009. Post Graduate of Medicine (PGIM), University of Colombo, Sri Lanka
Language: en
Type: Thesis
Abstract: Asthma has been identified as a leading cause of functional impairment especiafly among children and adolescents despite major therapeutic advancements. The magnitude of prevalence and cost of the disease have made asthma a priority concern among public health authorities across the world. Adolescents with asthma suffer not only due to the chronic and intermittent nature of the illness and but also by its management strategies. Research on asthma among adolescents is necessary to monitor disease trends, to identify factors associated with it. It is also important to evaluate how asthma affects the quality of life. The present study was carried out to determine the prevalence and correlates of asthma among 12- 14 year old school children and also to assess the impact of asthma on their quality of life (QOL). The study had two components; translation and validation of instruments on general and asthma specific quality of life and a cross sectional study to determine the prevalence and correlates of asthma. A case control design was used to assess the correlates of asthma and the association of asthma and atopy was examined using skin prick testing. The prevalence study was carried out among 1483 school children of 12-14 year age group in the district of Gampaha. A stratified multistage cluster sampling method was applied in selecting the study population. A self administered questionnaire was used to collect data on prevalence and QOL. Questions on asthma screening were adopted from the ISAAC tool and the QOL was assessed using the validated PedsQL tools. One hundred and fifty eight students, identified as having current asthma were enrolled for the case control study with two healthy controls per case from the same class. The study identified that being an only child (OR=4.2, 95 percent CI: 1.7-9.9); being the first born (OR=2.6 95 percent CI: 1.3-5.2); presence of allergic rhinitis (OR=2.7, 95 percent CI: 1.6-4.6) ; family history of asthma (OR= 1.8, 95 percent CI: 1.1-3.2) ; family history of allergic rhinitis (OR= 1.9, 95 percent CI: 1.1-3.2); family history of eczema (OR= 1.8, 95 percent CI: 1.0-3.2) and exposure to in-utero tobacco smoke (OR= 2.0, 95 percent CI: 1.06-3.7) as predictors of current asthma in this study sample. The skin prick testing, done with 61 current asthma cases-healthy sibling pairs revealed that adolescents with asthma show 9.3 times risk of atopy and have significant atopy towards cockroach (OR=5.3, 95 percent CI: 2.2-12.6), house dust mite (OR= 13.0, 95 percent CI: 3.08-54.7) and blomia (OR = 11.5,95 percent CI: 2.71-48.7). The study highlights the need to sensitize clinicians about the importance of measuring QOL in routine asthma management as a outcome measure. Translation and validation of the PedsQL battery of tools provides an opportunity for its use in clinical practice since the ultimate goal of treatment, is to improve the QOL of patients.
Description: Thesis for MD ( Community Medicine)
Keywords: MD ( Community Medicine)
Community Medicine
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Appears in Collections:PGIM Theses and Dissertations

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